Small and medium-sized businesses (SMBs) in Nigeria are at a crucial juncture with the rise of cloud computing, which offers significant opportunities for growth, efficiency, and innovation. Cloud services allow SMBs to access powerful computing without hefty upfront costs. Key benefits include cost efficiency, scalability, enhanced collaboration, improved security, and built-in disaster recovery solutions. However, challenges such as digital literacy, internet reliability, and regulatory compliance persist. As Nigeria's digital landscape evolves, education and awareness are essential for successful cloud adoption. Embracing cloud technology now can help Nigerian SMBs thrive in a competitive marketplace.